Marker selection for genetic case–control association studies
نویسندگان
چکیده
منابع مشابه
Multiobjective Genetic Marker Selection
A genetic mapping project, typically implemented during a search for genes responsible for a disease, requires the acquisition of a set of data from each of a large number of individuals. This data set includes the values of multiple genetic markers. These genetic markers occur at discrete positions along the genome, which is a collection of one or more linear chromosomes. Typing the value of a...
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Methods We have evaluated available English language articles from the past ten years (2001-2011). Initial search was performed through PubMed, Medline, and Google Scholar with key words such as: idiopathic scoliosis, gene, genetic, SNP, association studies. As a result, more than 700 papers were obtained. Research method of each study was assessed. We included only genetic association studies ...
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To the Editor: I am delighted to see that Arteriosclerosis, Thrombosis, and Vascular Biology has taken the lead in initiating an open discussion about genetic association studies in such a prominent manner. As correctly pointed out in the editorial by Dr Hegele,1 the number of publications has exponentially increased in the last decade. Despite the intrinsic problems with this approach, this ex...
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ژورنال
عنوان ژورنال: Nature Protocols
سال: 2009
ISSN: 1754-2189,1750-2799
DOI: 10.1038/nprot.2009.38